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These experiments indicated a pH optimum of pH 7.58 in the presence of 400 M MSA and 2 mM NAD +

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10.1371/journal.pgen.1007321 84 HirataY

Erythrocytes from knock-out mice that do not express the energy-sensing enzyme AMPK are significantly more susceptible to the eryptotic effect of energy depletion than erythrocytes from wild-type littermates expressing normal levels of AMPK [149]